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Stoldt VR, Sonneborn A, Leuker CE, Ernst JF: Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans , is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi
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for evidence, see the Lucky Strike ad campaign asking consumers "Do You Inhale?" from the 30's
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I went cold turkey the next day and havent smoked in the last 40 years
