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It has been concluded in a study that, a smoker having genital warts have a much greater chance of developing wart-virus associated cancers, including cervical cancer, vulval intraepitheial cancer, and penile cancer than a non-smoker
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The brand also gained cultural and political significance, famously linked to key revolutionary figures, cementing its status as a symbol of prestige and power

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It also may cause birth defects and male infertility in animals