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Description
This can happen when the lower esophageal sphincter (LES) muscle relaxes or weakens

Biochemically, rats exposed to nicotine (2.5 mL/kg) showed a significant increase of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) in serum due to hepatocyte cell death/damage

#17 Last week on our westbound Empire Builder there was no smoking lounge due to mechanical problems
I replaced it and that wonderful cold air came out once again
Tobacco smoke: Cigarettes and other tobacco products produce CO when burned, exposing both smokers and bystanders to the gas
