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Moreover, age of smoking ( = 0.16, P = 0.21), cigarettes per day ( = 0.08, P = 0.05), smoking cessation ( = 0.06, P = 0.18), smoking initiation ( = 0.01, P = 0.61), and alcohol consumption ( = 0.08, P = 0.20) indicated no significant association with the metabolic ratio of clozapine and norclozapine concentration (Supplementary Table 8)

The sites of a leukoplakia lesion that are preferentially biopsied are the areas that show induration (hardening) and erythroplasia (redness), and erosive or ulcerated areas

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It sends daily site parameters to the ARL for the trajectory model runs