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McDermott, MD, Jeremiah Stamler Professor and professor of medicine (general internal medicine and geriatrics) and preventive medicine at Northwestern University Feinberg School of Medicine, wrote in a related editorial

The long-term effects of tobacco addiction are as follows: Lung, throat, and mouth cancers Chronic obstructive pulmonary disease (COPD) Emphysema Heart disease Damaged blood vessels High cholesterol levels Premature death or reduced life expectancy Impact on Mental Health : Tobacco addiction has far-reaching effects on mental health, contributing to increased rates of anxiety , depression , and stress-related disorders , as mentioned in an article by the Mental Health Foundation titled Smoking and Mental Health. While many initially use tobacco as a way to cope with stress, it often worsens these mental health issues, creating a cycle of dependence and emotional turmoil

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For example, diacetyl has been linked to bronchiolitis obliterans (a disease that causes scarring within the lungs), while acetyl propionyl has been shown to cause airway inflammation in rats exposed by inhalation or ingestion

"Smoking any substance is not healthy, because combustion at high temperatures produces tar and carbon monoxide," he explains