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did native americans smoke tobacco American Use and Cultivation in Western North America Tobacco Use by Native Americans:
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It was also used as a stimulant to keep energy levels high

In light of the tremendous threat that tobacco use poses to health and the minimal risk that would be expected from banning menthol cigarettes, the risk/benefit calculation appears to favor a ban

Ultimately, the alien artifact theory for CSM in T he X-Files is creative, thoughtful, and works well

Source: The National Cancer Institute Almost half a million people [480,000] die from smoking related illnesses every year thats one in five of all deaths

It's left open-ended as to whether this lengthy backstory for CSM, whose real name is Carl Gerhard Busch according to The X-Files season 11, is true, but his final line in the episode suggests that at least some, if not most, of it is accurate.