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Description
Definition, epidemiology, and risk factors"
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In animal smoke exposure models, NLRP3 or GSDMD gene knockout mice exhibit reduced pulmonary inflammatory infiltration, decreased airway remodeling, and structural damage, further supporting the pathogenic role of pyroptosis in COPD progression at the in vivo level (96, 97)
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Barnes PJ, Burney PG, Silverman EK, Celli BR, Vestbo J, Wedzicha JA, et al
