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Description
Total testosterone measurement is performed via the isotope dilution liquid chromatography tandem mass spectrometry (ID-LC-MS/MS) method for routine quantitation of serum testosterone based on the National Institute for Standards and Technologys (NIST) reference method

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This means that psychiatrists will have no scientific data to estimate what serum levels work for individual patients and how smoking may affect therapeutic levels
Here he not only observed the process of smoking, but became addicted to it himself

In global terms, while the volume of cigarettes sold may have decreased, its value has increased
