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Certain factors may contribute to HS and worsen symptoms, such as: Obesity Smoking Hormones (this condition is more prevalent during and after puberty and prior to menopause) Genetics (HS runs in families about 33% of the time) Crohns disease may be linked to HS in rare instances Diagnosis of Hidradenitis Suppurativa Proper diagnosis of HS is crucial considering its symptoms often resemble other skin conditions