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Furthermore, the MD of FMD for exclusive combustible cigarette use versus non-use was similar to that for exclusive e-cigarette use versus non-use, suggesting that both of these products might have comparable adverse influences on endothelial health [MD of FMD (exclusive combustible cigarette use vs non-use): -1.21%

Nicotine molecules bind to the bodys nicotinic acetylcholine receptors, which are involved in regulating the dopamine reward system, and the resulting feel-good sensation is what makes nicotine addictive

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