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[31] After cigarette butts are discarded, they can leach toxins including nicotine, arsenic, polycyclic aromatic hydrocarbons and heavy metals into the environment

Regulation of neuronal nicotinic receptor traffic and expression

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After 24 weeks, Mini-Mental State Examination (MMSE) scores didnt significantly improve in the treatment groups compared to the placebo, and the placebo group actually improved significantly more than the B12-only group (Eussen, 2006)