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While IQOS is an electronic device, the FDA has classified it as a cigarette, which means the product is subject to all the same existing restrictions for traditional cigarettes

31 , documented that the compensatory increase in luteinizing hormone (LH) primarily increases SHBG which would, therefore, increase total testosterone

Centrifuge 8000 g for 10 min, take the supernatant, and extract the residue with 0.5 mL extraction solution for 2 h

The results confirmed that nicotine film enabled faster craving relief than the other dosage forms due to the rapid delivery of the full dose of 2.5 mg nicotine in 2 to 3 minutes

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