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Take the San Francisco e-cigarette startup JUUL, to name one, which advertises delicious flavors that promise to deliver a vapor experience like no other, all in the service of a lofty mission of helping adults to quit smoking

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Its casual export rate is almost equal to its inbound rate for those cigarettes smuggled commercially, according to our model

This chemical rewires the brain's reward system, creating powerful cravings and withdrawal symptoms like anxiety, irritability, and difficulty concentrating when use is stopped