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Called poly-use, the interplay between nicotine and alcohol can have a major effect on an individuals ability to quit either substance and stay quit

Microglia participate in functions central to neuroinflammation, (e.g., clearance of apoptotic cells and extracellular pathogens, removal of degenerating neurons and extracellular proteins, and cytokine/chemokine production [11])

& Guray, O

According to the January 2018 British Journal of Medicine in, the limited evidence available suggests e-cigs containing nicotine may help people quit smoking

PMID: 12461660
