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Description
The pigmentation may be the result of an increase in the number of melanocytes in the basal cell layer of the oral epithelium, or of increased melanin biosynthesis by the melanocytes
Rodenticides, while effective, can pose significant risks to both pets and wildlife

The nicotine is more concentrated in liquid form

Other causes include smoking, alcohol use, continuous exposure to hot beverages, and exposure to radiation therapy

It is likely that the pipes used during the Early Agricultural and Early Ceramic period saw similar uses
