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These findings suggest worse cardiovascular disease risk factors right after vaping or smoking, and activation of the sympathetic nervous system may play a role in the adverse responses seen immediately after using e-cigarettes and after exercise testing 90 minutes later. In the second analysis ( Abstract SA3142 - Differences In Treadmill Exercise Stress Testing Parameters Among Electronic Cigarette Vapers, Combustible Cigarette Smokers, And Controls: The Clues Study ) of the same participants, those who vaped and those who smoked were compared with the group of participants who did not smoke or use e-cigarettes to assess how they performed on exercise stress testing, which is known to predict cardiovascular disease outcomes