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American soldiers in World War II were provided with cigarettes, and many came home addicted

Historically, assessing the risks of long-term marijuana smoking under controlled clinical conditions has proven challenging for several reasons

According to the Australian Bureau of Statistics, in 2020-21, one in ten people (10.7% or 2.1 million people) aged 18 years and over were current daily smokers, with men more likely than women to smoke daily (12.6% compared to 8.8%)

UKB participants have lower indicators of health related characteristics, described as a healthy volunteer effect, that affects the generalizability of UKB research findings

Cigarette smoking is very common among people with mental disorders, especially those with schizophrenia