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Consistent with this, we observed downregulation of the mitochondrial urea cycle in tumor tissue compared with nontumor tissue in the TCGA HCC cohort (Supplemental Figure 4M)

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[3] Sour (cultured) cream, cultured buttermilk, and cultured butter are produced by inoculating pasteurized cream or milk with a lactic starter culture, churning (agitating) and holding the milk until a desired pH drop (or increase in acidity) is attained

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