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Second, while the full explanation for the male-female difference isn't yet fully understood, alcohol and nicotine have slightly different effects on men and women

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Within the latter group was a set of genes which play a crucial role in a molecular pathway regulating cell structure. The researchers then went on to investigate in more detail the altered expression of six selected genes within the pathway regulating cell structure in two brain regions, using 30 cases comprised again of smoking and non-smoking controls and alcohol abusers