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Framed as a bold call to action, it highlights the ongoing public health crisis caused by tobacco useresponsible for over 7 million deaths annuallyand its massive economic and social toll, especially in low- and middle-income countries

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For cardiovascular disease, smoking impairs endothelial function, reduces nitric oxide, and promotes atherosclerosis through oxidized LDL and effects on adhesion molecules (Kunierczyk 2023)

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