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Researchers know that nicotine in cigarettes affects your brain, including your mood

Research shows smokers have longer illnesses and worse symptoms than non-smokers

Moreover, mediators can interact with the nerve terminals or ion channels in the airways to inhibit or promote depolarisation, alter the response to activating stimuli, or lead to changes in gene expression modifying the function of the sensory fibre itself (Taylor-Clark & Undem, 2006)

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Iconic tobacco ads like the Marlboro Man thrived in print, emphasizing rugged individualism