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Moreover, fetal exposure to second-hand CS can suppress mucus production and augments Th2 polarization, resulting in increased susceptibility to allergic asthma and childhood respiratory infections in mice (Singh et al., 2011)

Summary and future perspectives p53 is a crucial tumour suppressor that protects cells from malignant transformation by activating a range of cellular responses, including apoptosis, adaptation of cellular metabolism, cell cycle arrest, cell senescence and DNA damage repair

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doi: 10.1186/s13578-023-01134-z 28 McAninchDMkelJALaHMHughesJNLovell-BadgeRHobbsRMet al