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The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD)

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What the Iroquois people would tell you is, We traded with each other a long time before any of you guys got here.' John, the Seneca entrepreneur, said that cigarettes had created a new class of entrepreneurs among a people who had been impoverished for generations, but that he wouldnt count on tobacco being part of the tribes economic solution for much longer