why are cigarettes so addictive Nicotine addiction explained — and how medications can help Why is tobacco so addictive?
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An open and closed pack of cigarettes

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8 It has been suggested that CS promotes M2 polarization of macrophages

Many hazardous biproducts of e-vapour have been identified as cardiovascular toxins such as Acetaldehyde, acrolein and formaldehyde 2 along with heavy metal traces 3

Pack years do not account for these differences
