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Yet another study on the topic published in the same journal suggests that the threat of relapse induced by smoking can last for as long as three years

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Day 3 is the hardest because nicotine fully clears the bloodstream by this point, and the brains withdrawal response peaks

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Participants were asked to self-report current smoking status, but how much people smoked also was determined by measuring cotinine, a nicotine byproduct that stays in the blood much longer than nicotine