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(I should perhaps note here that I am a lifelong blue-stater with only a passing familiarity with Toby Keith

Experimental and human models show that nicotine has acute analgesic effects that are mediated by the activation of nicotinic acetylcholine receptors (nAChRs) in the central and peripheral nervous systems [3,4,5,6]

Although the etiology of AEP remains unclear, multiple factors, including drugs, infections, and inhalation exposure, are thought to trigger the condition [3-5]

"Kentucky farmers don't want their children to get hooked on tobacco products while they're in middle school or high school any more than any parents anywhere want that to happen," McConnell said on the Senate floor

But understanding the danger and overcoming addiction are not the same thing