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United Kingdom: Public Health England continues to endorse vaping as a less harmful alternative to smoking

Additionally, if you have more receptors for certain chemicals (like caffeine), then it may take fewer puffs to feel their effects as well than someone who doesnt have as many receptors for those chemicals

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Accuracy and optimism in smokers' beliefs about quitting

A nicotine/smoking dose-response association has been observed for some bacterial taxa in gut flora, with an increasing mean relative abundance of specific taxa as cigarette packs per day increased 15