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and Nicotiana tabacum L.: a Comparative Study, Pakistan Journal of Botany

Since the 1950s, Defendants have researched and recognized, decades before the scientific community did, that nicotine is an addictive drug, that cigarette manufacturers are in the drug business, and that cigarettes are drug delivery devices. In this section of the Opinion, Judge Kessler discusses the evidence that for over 40 years, the Defendants' research had shown that the nicotine in tobacco causes cigarette smoking to be addictive

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Loose-leaf [edit] Loose-leaf chewing tobacco is the most widely available and most frequently used type of chewing tobacco

American Lung Association 2012)