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NF-B can repress p53 activity through upregulation of the p53 inhibitor MDM2 [73] Alternatively, the IB kinase (IKK), a major player in the canonical NF-B pathway, can induce post-translational modifications in the p53 protein, altering its stability [74] (Figure 4A)

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Born H, Persky M, Kraus DH, Peng R, Amin MR, Branski RC

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Moreover, MAPKs P38 and ERK increase the levels of SASP factors through NF-B transcriptional activity [21]

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"Marshall's Cubeb", Jim's Burnt Offerings , archived from the original on 2004-02-23, retrieved 2013-12-05

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Awan HM, Shah A, Rashid F, Shan G

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