does cigarette smoke set off carbon monoxide detectors Things That Trigger What's The Difference Between Smoke
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So yes, secondhand smoke can show up on a drug test, but in practical, everyday situations

This will remove not only the overwhelming smell but also the smoke residue

Coffee flavored vapes use food-grade flavorings to replicate the taste of coffee, so there's no actual caffeine, no coffee extract, and no stimulant effect

Uchiyama et al., 2013)
Drop Prohibition by Another Name Jeffrey Singer, an Arizona-based surgeon and senior fellow at the Cato Institute, has a better idea