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Cigarette smoking contributes to lung disease, cardiovascular diseases, and various cancers, while heavy alcohol consumption is linked to liver cirrhosis, breast cancer, and memory impairment

Compared with never-smokers, participants who were former or current smokers were older and were more likely to be male, and to have colon tumors that were dMMR and/or BRAF mutated (74)

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First, COPD patients have increased NKp44 ILC3(NCR ILC3) frequencies in their blood compared to control groups 27,28