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Therefore, while the sample size of women in this dataset was large, the proportions of former and current smokers were relatively small at 1.3% and 2.5%, respectively, and results should be interpreted with caution

Although this is a more conservative estimate, it reflects a realistic measure of the programs effectiveness in routine conditions and supports its relevance as a scalable self-help intervention

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The existing literature on lung cancer suggests a substantial booster effect of E-cigs on phase-I carcinogen-bioactivating enzymes, which increase the production of reactive oxygen species (ROS), as well as DNA oxidation, which produces 8-hydroxy-2-deoxyguanosine in rat models