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AB 3218's online sales provisions, effective January 1, 2025, prohibit DTC shipments of flavored vape products into California, and CDPH has extended that posture to flavored hemp-derived vapes that share an ENDS format

By contrast, in the Netherlands and Sweden, less than one in five daily smokers were heavy smokers see Figure 4

In fact, e-cigarette use grew 78% among high schoolers and 48% among middle schoolers in just one year from 2017 to 2018, and JUUL now accounts for three-quarters of the U.S

In the long-term, ZYNs can decrease energy levels by decreasing appetite and increasing energy expenditure

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