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While the exact ranking can vary, the top 10 causes of cancer generally include tobacco use, infections, alcohol consumption, air pollution, radiation exposure, occupational exposures, diet and physical activity, obesity, certain inherited genetic factors, and environmental pollutants

These products still derive their nicotine from tobacco leaves, meaning that they still fit under the nicotine inhalant delivery device definitions in Oregon for the purposes of regulation, and would be captured by the proposed restriction on flavored tobacco products if the Flavors Hook Oregon Kids coalition is successful in 2025, says Jamie Dunphy, a spokesman for the American Cancer Society Action Network

Battey JND, Szostak J, Phillips B, Teng C, Tung CK, Lim WT, et al

Surgeon General Report entitled How Tobacco Smoke Causes Disease and an overview is presented here