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A comprehensive comparison published in Scientific Reports identified 4,350 different compounds in tobacco smoke and 2,575 different compounds in marijuana smoke, but found only 231 in common

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For lung cancer, the risk was significantly lower in the younger decreasing light smokers than in the older group
Participants were asked about their smoking each year, which minimized recall bias and allowed us to model changes in smoking habits over time. Compared to those who never smoked, stable heavy smokers experienced the greatest decline in lung function as measured by FEV 1 , or the amount of air that can be forcibly exhaled in one second (-42.2 mL/year)