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Signs and symptoms of tobacco addiction tend to be more visible than manifestations of other substance use disorders

Downriver, Clark was having a more difficult time, as Lewis noted in his journal, "the river today they found streighter and more rapid even than yesterday, and the labour and difficulty of the navigation was proportionably increased, they therefore proceeded but slowly and with great pain as the men had become very languid from working in the water and many of their feet swolen and so painfull that they could scarcely walk." In the afternoon they arrived at the confluence of the rivers, but a beaver had cut down the note left by Lewis to take the middle fork, so Clark took the right fork, which seemed like the larger, more westerly route to follow

Men who use tobacco are at increased risk for many health problems, both short term and long term

Tobacco also was the crop that produced work and the first-earned money for many farm kids