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36 A recent study in the US found that non-daily smokers had substantially higher concentrations of urinary NNAL than non-smokers, with concentrations in the range that is associated with an increased risk of lung cancer

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Implications: E-cigarettes available at low, but not high, prices were stronger substitutes for legal, reduced-nicotine content cigarettes than illegal, normal-nicotine content cigarettes in a hypothetical reduced-nicotine tobacco market

Smuggled cigarettes make up substantial portions of cigarette consumption in many states, and greater than 25 percent of consumption in twelve states