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"It is possible that nicotine exposure, by increasing the release of dopamine, causes psychosis to develop." The association is clear, researchers said, however the lack of data regarding consumption of other substances, in addition to the effect of genetics and environment on the development of psychosis, requires further research to establish an explanation.

3 Cannabis use disorder is widely defined as problematic use of cannabis that results in significant distress or impairment with at least two issues within a 12-month period, like the substance use results in not being able to meet work, social, or familial obligations, or the substance use continues even after its affected or caused interpersonal issues

(2016, November 22)

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Problems with reproduction, pregnancy, and childbirth, such as infertility, early ( premature ) births, stillbirths, and birth defects