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Description
The first reports of trials with varenicline were published in 2006[62]
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November 6, 2011.
Only two studies (5%) were longitudinal observational studies 17,20 , while 9 (23%) were cross-sectional studies 14,16,19,21,23,24,30,32,38 , 1 (3%) was a case report 15 , and 27 (69%) were cell/ in vitro or animal studies 18,22,25-29,31,33-37,39-52

Philip Morris strategic interest in starters, as revealed in their internal corporate documentation, clearly contradicts the mature market hypothesis they have put forward