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When combined with smoking, the risk is magnified because the oesophageal and digestive cells are already vulnerable.Cigarettes contain nicotine along with thousands of harmful chemicals, many of which are toxic and carcinogenic

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Journal of Toxicology

E-cigarette proponents tout the reduced harm compared to tobacco products

The vapour is quite hot (especially from the modern devices, where the amount and quality of vapour are set manually), and the temperature itself irritates the users airways