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Quantification of tobacco minor alkaloids by GC-MS/MS Concentrations of minor tobacco alkaloids (nornicotine, myosmine, anatabine, anabasine, and isonicoteine) were determined (expressed as microgram per gram of sample (g/g)) using GC-Triple Quadruple Mass Spectrometry (MS/MS) in multiple reaction monitoring (MRM) mode

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Perhaps the enhanced fatigue resistance after smoking cessation is to some extent also attributable to the elevated haemoglobin concentration and haematocrit that enhance the oxygen carrying capacity and oxygen delivery with smoking cessation even above that seen in the non-smokers 17,53 , similar to that seen after doping with erythropoietin 71

The team applied an analytic approach called Mendelian randomisation, which uses genetic variants associated with an exposure (e.g