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Smoking affects HDL cholesterol specifically by inhibiting your bodys ability to produce it

Doubeni C, Li W, Fouayzi H, and DiFranza J

Consequently, the aim of this research is to understand the behaviors, risk perceptions, and views of adults who smoke with regard to tobacco use during the COVID-19 pandemic in Lebanon, a country with a high prevalence of tobacco use and a weak tobacco control policy framework

Ideally, to replicate the fulfilment you experienced from smoking you should choose an e-liquid with a total nicotine content that is representative of the intensity of your old smoking habit