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Studies distinguishing between e-cigarettes with and without nicotine found increases in endothelial progenitor cells, endothelial vesicles, plasma myeloperoxidase, arterial stiffness, changes in nicotine receptors, alveolar macrophages, and mononuclear phagocytes, leading to altered inflammatory responses and increased pulmonary susceptibility in users of nicotine-containing e-cigarettes (29, 41, 46)

Todays advance notice is a request for information, not a proposed rule, said Murray Garnick, general counsel for Altria Group

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