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Sirtuins, particularly SIRT1 and SIRT3, protect cells from oxidative stress by increasing the activity of antioxidant enzymes, including superoxide dismutase 2 (SOD2) and CAT (127, 131, 132)

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Data from this study indicates that smoking-related dysfunction of BBB endothelial physiology (e.g., increased oxidative stress, impaired tight junction expression/distribution, etc.) positively correlate with the total content of tar of various tobacco products and associated oxidative stress (ROS and NO output) rather than nicotine content

Drinking plenty of water: Try to drink at least eight glasses of fluids a day

This practice has become quite popular, especially among teens