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This occurs because the brain's receptors become less responsive to nicotine, requiring higher doses to produce the same dopamine release
PMC 5876835
Voltage-gated proton channel Hv1 regulates neuroinflammation and dopaminergic neurodegeneration in Parkinsons disease models
This specific smoke consists of two types: Sidestream smoke: Smoke emitted directly from a burning cigarette or cigar
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