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The samples were packaged in sterile bags and stored at 80 C until further analysis

Evidence indicates: No clear proof that heat not burn tobacco products are less harmful than cigarettes They are more harmful than nicotine vaping products Some harmful chemicals are present at higher levels than in conventional cigarettes No improvement in lung health has been observed among people who switch from smoking Use of heat not burn products is increasing: 2.6% of adults have ever tried them 0.9% currently use them Use among people who smoke has more than doubled since 2020 Past-month use among 1619 year olds increased three-fold between 2018 and 2023 Heat not burn tobacco products are regulated under the Tobacco and Related Products Regulations (2016), subject to tax, health warnings and age-of-sale restrictions