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States with the lowest smoking rates are generally located in the Northeast and the West, while states with the highest smoking rates are predominantly located in the South and Midwest

Quitting smoking is so hard because of the complex interplay between physical addiction to nicotine and the psychological habits formed around tobacco use, as studied in an article by the Centers for Disease Control and Prevention titled Why Quitting Smoking Is Hard. Physically, nicotine creates dependence by altering brain chemistry, leading to withdrawal symptoms such as irritability, cravings, and anxiety when a person tries to quit

Lung 194 , 281289 (2016)

Kot-Wasik, and J