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Experts say a combination of sky-high cigarette prices, historically lax enforcement and a laser-like focus on cutting smoking rates have combined in a perfect storm to fuel an explosion in Australia's black market

Nicotine replacement therapies (NRTs), such as nicotine patches, can help ease withdrawal symptoms

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Furthermore, the inhibitory effect of these chemicals on CYP2A6, although relatively weak in isolation, might be greater when the chemicals act in combination