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Mortality in low and middle-income countries, especially for women, will therefore continue to rise in the foreseeable future, even if efforts to reduce smoking are successful [ 11 ]

SP141 and MA242 (MDM2 inhibitors) are the potential drugs for treating HCC, because their effectiveness had been confirmed in breast cancer models and pancreatic tumor mice 153,154

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For people with asthma, these substances worsen airway inflammation and increase mucus production
1A, B, C, D) in endothelial cells exposed to tobacco smoke condensate, the expression of KU70/KU80 (Fig