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2000 titled Initial symptoms of nicotine dependence in adolescents. However, this time frame varies significantly based on several factors, including the frequency of use, the method of consumption (such as smoking or using smokeless tobacco), and genetic predisposition

Nicotine is released into the bloodstream through the skin and does not contain the cancer-causing chemicals produced by smoking

Data for 15 to 17 year olds was supressed (Appendix - Figure A3)

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Elements including metals in the atomizer and aerosol of disposable electronic cigarettes and electronic hookahs